What Are Long-Acting Injectables?
Long-acting injectables, or LAIs, release medication gradually and are administered on a schedule instead of requiring a daily pill. Depending on the medication, injections may be given weekly, monthly, or every several months.
Some LAIs treat schizophrenia, schizoaffective disorder, or bipolar I disorder. Others are used for alcohol or opioid use disorder. The approved diagnosis and schedule depend on the specific medication.
Who May Consider an LAI?
An LAI may be considered when fewer doses or scheduled care would better support treatment. For some patients and families, a scheduled injection can make it clearer when medication was received and reduce the need to track a daily dose.
Choosing an LAI is a personal decision that should be voluntary and based on informed consent. You remain central to the decision.
- Prefers fewer medication doses
- Has benefited from and tolerated an oral or related medication
- Wants structured, trackable care and can attend scheduled injection appointments
Choosing an LAI Together
The treatment team reviews diagnosis and treatment history, previous benefits and side effects, preferred schedule and injection route, monitoring and oral-medication requirements, medication availability, insurance coverage, and cost.
LAI formulations are not interchangeable. Initiation, oral overlap, observation, and missed-dose instructions vary by product.
- How will this affect my oral medications?
- What preparation or monitoring is required?
- What should I do if my dose is delayed?